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Nov 5, 2015. TechSmith Camtasia Studio 9.0.0 Build 1306 +. Serial Keys (1).rar.rar. Velikost. Incl.Keygen-TSZ.A consensus and refinement model for the prognostic relevance of Ki67 in breast cancer.
Surgical specimens of primary breast carcinoma from patients treated at the University of Munich, Ludwig-Maximilians University and the Ludwig-Maximilians University Hospital were analysed immunohistochemically for the proliferating cell nuclear antigen (PCNA) and Ki67, to examine the usefulness of Ki67 for the prediction of clinical outcome. The immunohistochemical results were compared with clinical data and were correlated with the ErbB2 oncogene status. Although the overall values were similar, a significant correlation between a positive correlation between Ki67 and PCNA was found (P = 0.0009), whereas no correlation was found between the ErbB2 oncogene status and Ki67 (P = 0.1). Based on a significant positive correlation between Ki67 and the PCNA and a significant negative correlation between the ErbB2 oncogene status and the PCNA, a refined scoring system for Ki67 is proposed. The prognostic relevance of this model was confirmed by Cox's univariate and multivariate analyses. Because Ki67 is considered a surrogate of cellular proliferation and because of the relationship between Ki67 and the PCNA, Ki67 is considered to be a useful prognostic marker in the immunohistochemical determination of breast cancer.Baron of Castleconnell
Baron Castleconnell was a title in the Peer ac619d1d87
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